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At around 8.10pm, police were called to reports of an altercation on the junction of Hitchin Road and Hucklesby Way, Luton.
A man in his 20s was taken to hospital having been stabbed. He sadly died shortly after arrival.
His attackers are described as two white men wearing dark clothing.
Detective Inspector Sam Khanna from the Bedfordshire, Cambridgeshire and Hertfordshire Major Crime Unit said: “Following an altercation in quite a busy area, the victim suffered fatal injuries.
“The man’s next of kin have been informed and are being supported by specialist officers.
“I'd urge anyone who saw what happened to get in touch.
“We are carrying out several lines of enquiry but are particularly keen to speak to anyone saw two men leaving the area at around this time.”
If you have any information or dashcam footage, please call 101 or report online quoting reference Operation Syphon.
You can also contact Crimestoppers anonymously on 0800 555 111 or visit the Crimestoppers website.
For further information about the work going on across Bedfordshire to tackle knife crime visit the Bedfordshire Violence and Exploitation Reduction Unit’s website.
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